St. Luke's Medical Towers, Texas Medical Center

From Intercontinental Airport:
  • Depart Intercontinental Airport onto Will Clayton
  • Take Will Clayton to US-59 South
  • Take US-59 S for 17 miles
  • Exit onto Fannin Street
  • After 2 miles, arrive at SLMT
From Hobby Airport:
  • Depart Hobby Airport onto Broadway
  • Take Broadway to I-45 North, take left exit #46B/Lake Jackson/Freeport/Victoria to TX-288 S
  • Take the Victoria exit onto US-59 South
  • Exit onto Fannin Street
  • After 2 miles, arrive at SLMT
From San Antonio:
  • Take I-10 East to I-610 South to US-59 North
  • Take the Main St. Exit, then turn right onto Fannin
  • After 2 miles, arrive at SLMT
From New Orleans:
  • Take I-10 West to US-59 South
  • Exit onto Fannin Street
  • After 2 miles, arrive at SLMT
From Dallas:
  • Take I-45 South to I-610 East
  • Take exit #20/Cleveland/Downtown to US-59 S
  • Exit onto Fannin Street
  • After 2 miles, arrive at SLMT